Study on the association of Vitamin D with glycaemic control in patients with type 2 diabetes mellitus

Abstract

Background: Type 2 diabetes mellitus (DM) is associated with increased morbidity and mortality due to the development of complications, especially due to poor glycaemic control. Besides its role in calcium homeostasis, Vitamin D is involved in the pathophysiology as well as glycaemic control of type 2 DM. Methods: Eighty patients diagnosed with type 2 DM were included. Vitamin D levels along with fasting blood sugar, post-prandial blood sugar, glycosylated haemoglobin and insulin were measured in all the individuals. Insulin resistance was calculated as homeostasis model for assessment of insulin resistance. Results: Vitamin D deficiency was observed in 52.5% of the patients. Vitamin D levels were not associated with markers of glycaemic control or insulin resistance. Conclusions: Hypovitaminosis D was observed in more than half of the patients with type 2 diabetes. suggesting a potential for vitamin D supplementation in type 2 DM patients.

Keywords

• diabetes mellitus
• glycated haemoglobin
• glycaemic control
• vitamin d