Nature Communications (Mar 2023)
Correlates of protection and viral load trajectories in omicron breakthrough infections in triple vaccinated healthcare workers
- Ulrika Marking,
- Sebastian Havervall,
- Nina Greilert Norin,
- Oscar Bladh,
- Wanda Christ,
- Max Gordon,
- Henry Ng,
- Kim Blom,
- Mia Phillipson,
- Sara Mangsbo,
- Jessica J. Alm,
- Anna Smed-Sörensen,
- Peter Nilsson,
- Sophia Hober,
- Mikael Åberg,
- Jonas Klingström,
- Charlotte Thålin
Affiliations
- Ulrika Marking
- Department of Clinical Sciences, Karolinska Institutet Danderyd Hospital
- Sebastian Havervall
- Department of Clinical Sciences, Karolinska Institutet Danderyd Hospital
- Nina Greilert Norin
- Department of Clinical Sciences, Karolinska Institutet Danderyd Hospital
- Oscar Bladh
- Department of Clinical Sciences, Karolinska Institutet Danderyd Hospital
- Wanda Christ
- Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet
- Max Gordon
- Department of Clinical Sciences, Karolinska Institutet Danderyd Hospital
- Henry Ng
- Department of Medical Cell Biology and SciLifeLab, Uppsala University
- Kim Blom
- Department of Clinical Sciences, Karolinska Institutet Danderyd Hospital
- Mia Phillipson
- Department of Medical Cell Biology and SciLifeLab, Uppsala University
- Sara Mangsbo
- Department of Pharmacy and SciLifeLab, Uppsala University
- Jessica J. Alm
- Department of Microbiology, Tumor and Cell Biology & National Pandemic Center, Karolinska Institutet
- Anna Smed-Sörensen
- Division of Immunology and Allergy, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital
- Peter Nilsson
- Department of Protein Science, KTH Royal Institute of Technology, SciLifeLab
- Sophia Hober
- Department of Protein Science, KTH Royal Institute of Technology, SciLifeLab
- Mikael Åberg
- Department of Medical Sciences, Clinical Chemistry and SciLifeLab, Uppsala University
- Jonas Klingström
- Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet
- Charlotte Thålin
- Department of Clinical Sciences, Karolinska Institutet Danderyd Hospital
- DOI
- https://doi.org/10.1038/s41467-023-36984-1
- Journal volume & issue
-
Vol. 14,
no. 1
pp. 1 – 10
Abstract
Correlation between vaccine induced serological response and protection against SARS-CoV-2 omicron infection is not well understood. Authors investigate breakthrough infections in triple-vaccinated healthcare workers, to characterise correlates of protection and viral characteristics.
