Assessment of the severity of ulcerative colitis: An effective pathway from invasive to non-invasive diagnosis

Abstract

The purpose of the study is to study the Diagnostic and prognostic importance of TGF-β2 in patients with ulcerative colitis with different severity. The study received 82 patients with stasionar and outpatient treated ulcerative colitis in the Gastroenterology Department of Bukhara regional Multidisciplinary Medical Center during 2021-2023 and 20 health professionals as a control group. Patients were diagnosed with serum immunoferment analysis using IL-6 and TGF-β2, and its importance was studied. The results of the study showed an increase in IL-6 and a decrease in TGF-β2 in severe types of ulcerative colitis, and found that it could be used in diagnosis as a poor prognostic marker.