Immunological aspects of unrelated bone marrow transplantation: alloreactivity and immunoreconstitution

Abstract

The main complications after bone marrow transplantation (BMT) are graft versus host disease (GvHD), post-transplant viral infections and disease relapse. The underlying causes of these problems are the degree of HLA matching between donor and patient and the rate of immune reconstitution.

Keywords

• Bone marrow transplantations
• HLA matching
• alloreativity
• immune reconstrution