Anais Brasileiros de Dermatologia (Oct 2016)

Linear IgA and IgG bullous dermatosis

  • Karina de Almeida Pinto Fernandes,
  • Kely Hernández Galvis,
  • Anndressa Camillo da Matta Setubal Gomes,
  • Osvania Maris Nogueira,
  • Paulo Antônio Oldani Felix,
  • Thiago Jeunon de Sousa Vargas

DOI
https://doi.org/10.1590/abd1806-4841.20164630
Journal volume & issue
Vol. 91, no. 5 suppl 1
pp. 32 – 34

Abstract

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Abstract Childhood linear immunoglobulin A dermatosis is a rare autoimmune vesiculobullous disease. It results in linear deposition of autoantibodies (immunoglobulin A) against antigens in the basal membrane zone, leading to subepidermal cleavage. Additional depositions of immunoglobulin G and complement-3 might occur. It is still debated whether concomitant findings of immunoglobulins A and G should be considered a subtype of this dermatosis or a new entity. Further studies are needed to recognize this clinical variant.

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