Acta Crystallographica Section E (Feb 2011)

1-[2-(4-Nitrophenyl)-5-(5-phenyl-1,2-oxazol-3-yl)-1,2,3,4-tetrahydroquinolin-4-yl]pyrrolidin-2-one

  • Margarita Gutierrez,
  • Luis Astudillo,
  • Luisa Quesada,
  • Iván Brito,
  • Matías López-Rodríguez

DOI
https://doi.org/10.1107/S1600536810054048
Journal volume & issue
Vol. 67, no. 2
pp. o308 – o309

Abstract

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The title compound, (I) C28H24N4O4, is the trans diastereoisomer of the compound 1-[2-(4-nitrophenyl)-6-(5-phenyl-3-isoxazolyl)-1,2,3,4-tetrahydro-4-quinolinyl]-2-pyrrolidinone monohydrate, (II) [Gutierrez et al. (2011). Acta Cryst. E67, o175–o176]. The most obvious differences between the diastereoisomers are the dihedral angles between the isoxazole ring and the benzene and phenyl rings [47.0 (2); 56.4 (2) and 33.3 (2); 11.0 (2)°, respectively, for (II) 75.4 (2) and 5.8 (3), respectively, for (I)]. In the crystal of (I), the molecules are linked by N—H...O interactions into a chain along [001] with graph-set notation C(8).