Journal of Stress Physiology & Biochemistry (Dec 2017)

Haemolymph of Cold-Adapted Baikal Endemic Amphipods as a Promising Source for Screening of Novel Natural Products

  • Axenov-Gribanov D.V. ,
  • Protasov E.S.,
  • Voytsekhovskaya I.V.,
  • Shatilina Z.M.,
  • Rzhechitskiy Y.A.,
  • Dimova M.D.,
  • Kostka D.V.,
  • Lubyaga Y.A.,
  • Timofeyev M.A.

Journal volume & issue
Vol. 13, no. 4
pp. 74 – 80

Abstract

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The aim of this study was to assess the possibility to use Baikal endemic amphipods as a source for screening of novel natural products. Analysis of amphipod’s E. verrucosus hemolymph by HPLC-MS was performed for the first time. A number of natural products with new molecular mass for Baikal endemic macroinvertebrates were found. We found a compound as chrysin by comparison of MS1, MS2 profiles and molecular mass of natural products registered in Dictionary of Natural Products and MZ-cloud databases. Also, we found new compound with mass 493.80277 Da, circulating in the amphipod’s hemolymph.

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