Two Additional New Compounds from the Marine-Derived Fungus Pseudallescheria ellipsoidea F42-3
Kun-Teng Wang,
Meng-Yang Xu,
Wei Liu,
Hou-Jin Li,
Jun Xu,
De-Po Yang,
Wen-Jian Lan,
Lai-You Wang
Affiliations
Kun-Teng Wang
School of Pharmacy, Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China
Meng-Yang Xu
School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China
Wei Liu
School of Pharmacy, Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China
Hou-Jin Li
School of Chemistry and Chemical Engineering, Sun Yat-sen University, Guangzhou 510275, China
Jun Xu
School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China
De-Po Yang
School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China
Wen-Jian Lan
School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China
Lai-You Wang
School of Pharmacy, Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China
Two additional new compounds, pseudellone D (1) and (5S,6S)-dihydroxylasiodiplodin (3), along with the two known compounds lasiodipline F (2), (5S)-hydroxylasiodiplodin (4) were isolated from the marine-derived fungus Pseudallescheria ellipsoidea F42-3 associated with the soft coral Lobophytum crassum. Their structures, including absolute configurations, were elucidated on the basis of the corresponding spectroscopic data and electronic circular dichroism (ECD) spectra.
