P573: PHARMACOKINETIC EXPOSURE EQUIVALENCE AND PRELIMINARY EFFICACY AND SAFETY FROM A RANDOMIZED CROSS OVER PHASE 3 STUDY OF AN ORAL HYPOMETHYLATING AGENT DEC-C COMPARED TO IV DECITABINE IN AML PATIENTS

• K. Geissler,
• Z. Koristek,
• T. Bernal del Castillo,
• J. Novák,
• G. Rodriguez Macias,
• S. K. Metzelder,
• A. Illes,
• A. Nagy,
• J. Mayer,
• M. Arnan,
• M.-M. Keating,
• J. Krauter,
• M. Lunghi,
• N. Stefano Fracchiolla,
• U. Platzbecker,
• V. Santini,
• Y. Sano,
• A. Oganesian,
• H. Keer,
• M. Lübbert

Affiliations

K. Geissler

1 Clinic Hietzing, Vienna, Austria

Z. Koristek

2 University Hospital Ostrava, Ostrava, Czechia

T. Bernal del Castillo

3 Hospital Universitario Central de Asturias, Oviedo, Spain

J. Novák

4 Department of Haematology, 3rd Faculty of Medicine, Charles University and Faculty Hospital Kralovske Vinohrady, Prague, Czechia

G. Rodriguez Macias

5 Hospital General Universitario Gregorio Marañón, Madrid, Spain

S. K. Metzelder

6 Philipps-Universität Marburg, Marburg, Germany

A. Illes

7 Division of Haematologoy, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, Debreccen

A. Nagy

8 1st Department of Internal Medicine, University of Pécs, Pécs, Hungary

J. Mayer

9 Fakultní Nemocnice, Brno, Czechia

M. Arnan

10 Hematology Department, Servei d’Hematologia, Institut Català d’Oncologia, Hospital Duran i Reynals, Institut d’Investigació Biomèdica de Bellvitge (IDIBELL), Universitat de Barcelona, L’Hospitalet de Llobregat, Barcelona, Spain

M.-M. Keating

11 Queen Elizabeth II (QEII) Health Sciences Centre, Halifax, Nova Scotia, Canada

J. Krauter

12 Städtisches Klinikum Braunschweig, Braunschweig, Germany

M. Lunghi

13 Azienda Ospedaliero-Universitaria Maggiore della Carità Novara, Novara

N. Stefano Fracchiolla

14 Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico di Milano, Milano, Italy

U. Platzbecker

15 University Hospital Leipzig, Leipzig, Germany

V. Santini

16 MDS Unit, AOU Careggi, DMSC, University of Florence, Firenze, Italy

Y. Sano

17 Astex Pharmaceuticals, Inc., Pleasanton, United States of America

A. Oganesian

17 Astex Pharmaceuticals, Inc., Pleasanton, United States of America

H. Keer

17 Astex Pharmaceuticals, Inc., Pleasanton, United States of America

M. Lübbert

18 Universitaetsklinikum Freiburg, Freiburg, Germany