PLoS ONE (Jan 2024)

Tuberculosis patients face high treatment support costs in Colombia, 2021.

  • Oscar Andrés Cruz Martínez,
  • Ingrid García,
  • Gloria Mercedes Puerto,
  • Nelson J Alvis-Zakzuk,
  • Martha Patricia López,
  • Juan Carlos Moreno Cubides,
  • Ángela María Sánchez Salazar,
  • Julián Trujillo Trujillo,
  • Claudia Marcela Castro-Osorio,
  • Vivian Vanessa Rubio,
  • Carlos Castañeda-Orjuela,
  • Ernesto Montoro,
  • Peter Nguhiu,
  • Inés García Baena

DOI
https://doi.org/10.1371/journal.pone.0296250
Journal volume & issue
Vol. 19, no. 4
p. e0296250

Abstract

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ObjectiveTo estimate the baseline to measure one of the three indicators of the World Health Organization (WHO) End TB strategy (2015-2035), measure the costs incurred by patients affected by tuberculosis (TB) during a treatment episode and estimate the proportion of households facing catastrophic costs (CC) and associated risk factors, in Colombia, 2021.Material and methodsA nationally representative cross-sectional survey was conducted among participants on TB treatment in Colombia, using telephone interviews due to the exceptional context of the COVID-19 pandemic. The survey collected household costs (direct [medical and non-medical out-of-pocket expenses] and indirect) over an episode of TB, loss of time, coping measures, self-reported income, and asset ownership. Total costs were expressed as a proportion of annual household income and analyzed for risk factors of CC (defined as costs above 20% annual household income).ResultsThe proportion of TB-affected households incurring in costs above 20% annual household income (CC) was 51.7% (95%CI: 45.4-58.0) overall, 51.3% (95%CI: 44.9-57.7) among patients with drug-sensitive (DS) TB, and 65.0% (95%CI: 48.0-82.0) among drug-resistant (DR). The average patient cost of a TB case in Colombia was $1,218 (95%CI 1,106-1,330) including $860.9 (95%CI 776.1-945.7) for non-medical costs, $339 (95%CI 257-421) for the indirect costs, and $18.1 (95%CI 11.9-24.4) for the medical costs. The factors that influenced the probability of facing CC were income quintile, job loss, DR-TB patient, and TB type.ConclusionMain cost drivers for CC were non-medical out-of-pocket expenses and income loss (indirect costs). Current social protection programs ought to be expanded to mitigate the proportion of TB-affected households facing CC in Colombia, especially those with lower income levels.