CYP6AE gene cluster knockout in Helicoverpa armigera reveals role in detoxification of phytochemicals and insecticides

Huidong Wang; Yu Shi; Lu Wang; Shuai Liu; Shuwen Wu; Yihua Yang; René Feyereisen; Yidong Wu

doi:10.1038/s41467-018-07226-6

Nature Communications (Nov 2018)

CYP6AE gene cluster knockout in Helicoverpa armigera reveals role in detoxification of phytochemicals and insecticides

Huidong Wang,
Yu Shi,
Lu Wang,
Shuai Liu,
Shuwen Wu,
Yihua Yang,
René Feyereisen,
Yidong Wu

Affiliations

Huidong Wang: College of Plant Protection, Nanjing Agricultural University
Yu Shi: College of Plant Protection, Nanjing Agricultural University
Lu Wang: College of Plant Protection, Nanjing Agricultural University
Shuai Liu: College of Plant Protection, Nanjing Agricultural University
Shuwen Wu: College of Plant Protection, Nanjing Agricultural University
Yihua Yang: College of Plant Protection, Nanjing Agricultural University
René Feyereisen: Department of Plant and Environmental Sciences, University of Copenhagen
Yidong Wu: College of Plant Protection, Nanjing Agricultural University

DOI: https://doi.org/10.1038/s41467-018-07226-6
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 8

Abstract

Read online

Cotton bollworm is an important agricultural pest with widespread resistance to insecticides. Here Wang et al. identifies CYP6AEs from cotton bollworm involved in detoxifying plant toxins and chemical insecticides through the CRISPR-Cas9-based reverse genetics approach in conjunction with in vitro metabolism.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal