SERUM AND SALIVARY ENZYMES – POSSIBLE INDICATOR OF THE INCIDENCE OF TOOTH DECAY IN PATIENTS WITH CHRONIC ALCOHOLIC HEPATITIS

Abstract

Objectives. Determination of correlations between the cariogenic index, as quantifying element for the frequency of tooth decay, and some salivary and serum enzymes in patients who had been diagnosed with chronic alcoholic hepatitis. Materials and methods. The study group consisted of 25 patients diagnosed with chronic alcoholic hepatitis. The following salivary enzymes were determined: AST, ALT and the AST/ALT ratio. Also, the following plasma enzymes were determined: AST, ALT, amylase, LDH, GGT, ALP, AST/ALT and GGT/ALP ratios. Results. The determined average values were: cariogenic index 1,8±0,96, salivary AST 72,52±46,21 U/L, salivary ALT 80,28±40,34 U/L, salivary AST/ALT ratio 1,03±0,63, plasma AST 115,80±79,16 U/L, plasma ALT 114,76±116,01 U/L, plasma LDH 546,88±444,08 U/L, plasma amylase 53,04±18,12U/L, plasma GGT 212,32±198,12 U/L, plasma ALP 98,76±30,88 U/L, plasma AST/ALT ratio 1,58±1,17, plasma GGT/ALP ratio 2,15±1,76. Conclusions. Statistically significant correlations were determined between the cariogenic index and the salivary AST/ALT ratio, plasma AST, plasma ALT, plasma AST/ALT ratio.

Keywords

• chronic alcoholic hepatitis
• cariogenic index
• salivary enzymes
• plasma enzymes