Química Nova (Jan 2010)

Lychnophorinae (asteraceae): a survey of its chemical constituents and biological activities

  • Larissa Costa Keles,
  • Nathalya Isabel de Melo,
  • Gabriela de Paula Aguiar,
  • Kamila Akemi Lima Wakabayashi,
  • Carlos Eduardo de Carvalho,
  • Wilson Roberto Cunha,
  • Antônio Eduardo Miller Crotti,
  • João Luis Callegari Lopes,
  • Norberto Peporine Lopes

DOI
https://doi.org/10.1590/S0100-40422010001000038
Journal volume & issue
Vol. 33, no. 10
pp. 2245 – 2260

Abstract

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This work reviews the current literature about the chemical constituents and the biological activities of the subtribe Lychnophorinae (Vernonieae, Asteraceae). The notable secondary metabolites are sesquiterpene lactones of furanoheliangolide (goyazensolide and eremantholide types) and flavonoids. Some of its most investigated activities include its anti-inflammatory, analgesic, antimicrobial and cytotoxic activities, specially for the Lychnophora and Eremanthus species. The data presented on this paper not only displayed the role played by the Lychnophorinae species as a source of bioactive compounds, but also reinforced the need of further studies involving the species of such subtribe.

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