Data in Brief (Jun 2017)

Cytokine data obtained from synovial stromal cells of patients with rheumatoid arthritis or osteoarthritis

  • Johanna A. Huhtakangas,
  • Johanna Veijola,
  • Sanna Turunen,
  • Anna Karjalainen,
  • Maarit Valkealahti,
  • Tomi Nousiainen,
  • Susanna Yli-Luukko,
  • Olli Vuolteenaho,
  • Petri Lehenkari

DOI
https://doi.org/10.1016/j.dib.2017.04.041
Journal volume & issue
Vol. 12, no. C
pp. 593 – 602

Abstract

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In this article, we share the raw cytokine data obtained from basal and stimulated synovial stromal cells cultured from patients with rheumatoid arthritis or osteoarthritis. This data article is related to the research article entitled “1,25D3 and calcipotriol, its hypocalcemic analog, exert a long-lasting anti-inflammatory and anti-proliferative effect in synoviocytes cultured from patients with rheumatoid arthritis and osteoarthritis (1). Cytokine levels were analyzed by a magnetic bead–based multiplex assay (a panel of 27 important cytokines) in two separate sets of experiments. The first was conducted with IL-1β and 1,25(OH)2D3 and the other with TNFα, calcipotriol, i.e. the hypocalcemic analog 1,25(OH)2D3, and dexamethasone. The raw data of this article display the individual variation in basal secretion of cytokines and in their response to different stimuli.

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