MALT lymphoma of the palatal minor salivary Grand in patient with Sjögren's syndrome: A case report

Abstract

We present a quite rare case of MALT lymphoma originating from the palatal minor salivary gland in a 37-year-old woman with Sjögren's syndrome (SS). She underwent an excision biopsy and definite diagnosis of MALT lymphoma was obtained on the basis of microscopic finding with lymphoepithelial lesion, immunohistochemistry positive for CD20 and negative for CD3, CD5, cycclinD1, and detection of immunoglobulin light chain restriction with kappa light-chain restricted monoclonality. MALT lymphoma is considered in the differential diagnosis of a painless, non-ulcerative palatal swelling. In this case, SS remained undiagnosed until after MALT lymphoma diagnosis. Patients with MALT lymphoma in the minor salivary glands need to be investigated for SS even if there is no clinical symptom of SS. Surgical excision can be recommended in case of limited stages resulting in good prognosis.

Keywords

• MALT lymphoma
• Hard palate
• Minor salivary gland
• Sjogren's syndrome