Iranian South Medical Journal (Dec 2009)
The investigation effect of heparin infusion on plasma glucose and Lactate during submaximal exercise
Abstract
Background: Many investigations have demonstrated that increasing fat availability increases fat oxidation and decreases carbohydrate use in the whole body and skeletal muscle. The purpose of this study was to determine the effect of heparin infusion on some influential factors in aerobic metabolism and performance during submaximal cycling. Methods: Thirty healthy males (15 as control and 15 as target group) cycled for 20 min at 70% maximal O2 uptake (VO2max) in two separate stages (baseline and infusion of heparin or lactose. Blood samples were drawn immediately followed up exercise for calculating plasma glucose and lactate concentration and lactate dehydrogenase activity (LDH). VO2max also monitored. The finding are compared by T test (Independent-sample and Paired- samples T test) in two groups (P<0.05). Results: The finding showed that heparin infusion had not influence on plasma glucose, lactate concentration, and LDH activity (P<0.05). Also VO2max and heart rate had not significantly changed in posttest condition compare to pretest (P<0.05). Conclusion: Our findings suggested that heparin infusion is not affect aerobic capacity and carbohydrate substrate utilization during submaximal exercise. Additional investigation is required to directly identify these supplementations on the substrate utilization and fat-carbohydrate metabolism and exercise performance.
