Association of polymorphism apolipoprotein A1 with the lipid profile serum

Abstract

Objective: to investigate apolipoprotein AI gene polymorphism and its associations with lipid profile in Caucasian population of West Siberia. The study included 100 persons with total cho lesterol >300 mg/dl, 100 – with total cholesterol А of APOAI gene and some key lipid risk factors (total blood cholesterol, low density lipoproteins cholesterol, index of atherogenity) in people of West-Siberian region. The genotype AA has been associated with higher blood lipid levels in population of West Siberia.

Keywords

• apolipoprotein ai gene
• hdl
• high-density lipoprotein cholesterol
• promoter polymorphism
• plasma lipids
• population