Emerging Infectious Diseases (Jun 2003)

Tick-Borne Encephalitis with Hemorrhagic Syndrome, Novosibirsk Region, Russia, 1999

  • Vladimir A. Ternovoi,
  • Gennady P. Kurzhukov,
  • Yuri V. Sokolov,
  • Gennady Y. Ivanov,
  • Vladimir A. Ivanisenko,
  • Alexander V. Loktev,
  • Robert W. Ryder,
  • Sergey V. Netesov,
  • Valery B. Loktev

DOI
https://doi.org/10.3201/eid0906.030007
Journal volume & issue
Vol. 9, no. 6
pp. 743 – 746

Abstract

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Eight fatal cases of tick-borne encephalitis with unusual hemorrhagic syndrome were identified in 1999 in the Novosibirsk Region, Russia. To study these strains, we sequenced cDNA fragments of protein E gene from six archival formalin-fixed brain samples. Phylogenetic analysis showed tick-borne encephalitis variants clustered with a Far Eastern subtype (homology 94.7%) but not with the Siberian subtype (82%).

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