DNA–melamine hybrid molecules: from self-assembly to nanostructures

Abstract

Single-stranded DNA–melamine hybrid molecular building blocks were synthesized using a phosphoramidation cross-coupling reaction with a zero linker approach. The self-assembly of the DNA–organic hybrid molecules was achieved by DNA hybridization. Following self-assembly, two distinct types of nanostructures in the form of linear chains and network arrays were observed. The morphology of the self-assembled nanostructures was found to depend on the number of DNA strands that were attached to a single melamine molecule.

Keywords

• DNA–organic hybrid
• melamine
• nanostructures
• phosphoramidation
• self-assembly