Journal of Cardiothoracic Surgery (May 2012)

Impact of patient-prosthesis mismatch on 30-day outcomes in young and middle-aged patients undergoing aortic valve replacement

  • Hernández-Vaquero Daniel,
  • Llosa Juan C,
  • Díaz Rocío,
  • Khalpey Zain,
  • Morales Carlos,
  • Álvarez Rubén,
  • López Jose,
  • Boye Francisco

DOI
https://doi.org/10.1186/1749-8090-7-46
Journal volume & issue
Vol. 7, no. 1
p. 46

Abstract

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Abstract Background The impact of patient-prosthesis mismatch (PPM) on early outcomes in young and middle-aged patients undergoing conventional aortic valve replacement for severe aortic stenosis remains unknown. Our objective was to evaluate the incidence of some degree of PPM and its influence on early mortality and morbidity. Methods We analyzed our single center experience in all patients 2/m2. The influence of PPM on early mortality and postoperative complications was studied using propensity score analysis. Follow up at 30 postoperative days was 100% complete. Results Of 199 patients studied, 61 (30,7%) had some degree of PPM. PPM was associated with an increased postoperative mortality (OR = 8,71; 95% CI = 1,67–45,29; p = 0,04) and major postoperative complications (OR = 2,96; CI = 1,03–8,55; p = 0,044). However, no association between PPM and prolonged hospital or ICU stay was demonstrated. Conclusions Moderate PPM is a common finding in young and middle-aged patients undergoing surgery for aortic valve replacement due to severe stenosis. In addition, its influence on early outcomes may be relevant.

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