INFLUENCE OF COMPENSATION OF SELENIUM DEFICIENCY ON IMMUNOLOGICAL PARAMETERS OF PATIENTS WITH MULTIDRUG-RESISTANT TUBERCULOSIS AT THE BACKGROUND OF SUBCLINICAL HYPOTHYROIDISM

Abstract

In 60 patients with multidrug-resistant tuberculosis at the background of subclinical hypothyroidism serum level ofselenium, thyroid state and immunological parameters were studied in dynamic of the intensive phase of chemotherapy.Initially low level of selenium, subclinical hypothyroidism and weaken immunological response toward tuberculosis werediagnosed. Prescribing of selenite sodium with 200 µ daily during 60 daily doses normalized serum level of selenium,restored thyroid function and improved immunological response. Using of selenite sodium like an accompanying medicine during chemotherapy of multidrug tuberculosis at the background of subclinical hypothyroidism after estimation ofserum level of selenium is recommended.

Keywords

• multidrug-resistant tuberculosis
• thyroid gland
• sodium selenite
• chemotherapy