Measuring Exhaled Propofol in an Ex Vivo Lung Model with Low-Cost Metal Oxide Gas Sensors
Christian Bur,
Ksenia Karst,
Andreas Schütze,
Felix Maurer,
Stefan Radermacher,
Klaus Hoffmann,
Sascha Kreuer
Affiliations
Christian Bur
Lab for Measurement Technology, Saarland University, 66123 Saarbrücken, Germany
Ksenia Karst
Lab for Measurement Technology, Saarland University, 66123 Saarbrücken, Germany
Andreas Schütze
Lab for Measurement Technology, Saarland University, 66123 Saarbrücken, Germany
Felix Maurer
CBR—Center of Breath Research, Department of Anesthesiology, Intensive Care and Pain Therapy, Saarland University Medical Center and Saarland University, 66424 Homburg, Germany
Stefan Radermacher
CBR—Center of Breath Research, Department of Anesthesiology, Intensive Care and Pain Therapy, Saarland University Medical Center and Saarland University, 66424 Homburg, Germany
Klaus Hoffmann
CBR—Center of Breath Research, Department of Anesthesiology, Intensive Care and Pain Therapy, Saarland University Medical Center and Saarland University, 66424 Homburg, Germany
Sascha Kreuer
CBR—Center of Breath Research, Department of Anesthesiology, Intensive Care and Pain Therapy, Saarland University Medical Center and Saarland University, 66424 Homburg, Germany
Herein, commercially available MOS gas sensors running in temperature cycling operations are studied for the online monitoring of propofol in an ex vivo ventilation and perfusion lung model. A porcine lung was connected to a heart–lung machine and propofol was added into the blood reservoir. The MOS sensor was able to quantitatively detect exhaled propofol in the very low ppb range. The results are in accordance with those obtained by a propofol-sensitive ion mobility spectrometer.
