Nature Communications (Jan 2021)
Analysis of SARS-CoV-2 antibodies in COVID-19 convalescent blood using a coronavirus antigen microarray
- Rafael R. de Assis,
- Aarti Jain,
- Rie Nakajima,
- Algis Jasinskas,
- Jiin Felgner,
- Joshua M. Obiero,
- Philip J. Norris,
- Mars Stone,
- Graham Simmons,
- Anil Bagri,
- Johannes Irsch,
- Martin Schreiber,
- Andreas Buser,
- Andreas Holbro,
- Manuel Battegay,
- Philip Hosimer,
- Charles Noesen,
- Oluwasanmi Adenaiye,
- Sheldon Tai,
- Filbert Hong,
- Donald K. Milton,
- D. Huw Davies,
- Paul Contestable,
- Laurence M. Corash,
- Michael P. Busch,
- Philip L. Felgner,
- Saahir Khan
Affiliations
- Rafael R. de Assis
- Department of Physiology and Biophysics, School of Medicine, University of California
- Aarti Jain
- Department of Physiology and Biophysics, School of Medicine, University of California
- Rie Nakajima
- Department of Physiology and Biophysics, School of Medicine, University of California
- Algis Jasinskas
- Department of Physiology and Biophysics, School of Medicine, University of California
- Jiin Felgner
- Department of Physiology and Biophysics, School of Medicine, University of California
- Joshua M. Obiero
- Department of Physiology and Biophysics, School of Medicine, University of California
- Philip J. Norris
- Vitalant Research Institute
- Mars Stone
- Vitalant Research Institute
- Graham Simmons
- Vitalant Research Institute
- Anil Bagri
- Cerus Corporation
- Johannes Irsch
- Cerus Corporation
- Martin Schreiber
- Department of Surgery, Oregon Health & Science University
- Andreas Buser
- Division of Infectious Diseases & Hospital Epidemiology, University Hospital Basel, University of Basel
- Andreas Holbro
- Department of Surgery, Oregon Health & Science University
- Manuel Battegay
- Division of Infectious Diseases & Hospital Epidemiology, University Hospital Basel, University of Basel
- Philip Hosimer
- Ortho Clinical Diagnostics
- Charles Noesen
- Ortho Clinical Diagnostics
- Oluwasanmi Adenaiye
- Institute for Applied Environmental Health, School of Public Health, University of Maryland
- Sheldon Tai
- Institute for Applied Environmental Health, School of Public Health, University of Maryland
- Filbert Hong
- Institute for Applied Environmental Health, School of Public Health, University of Maryland
- Donald K. Milton
- Institute for Applied Environmental Health, School of Public Health, University of Maryland
- D. Huw Davies
- Department of Physiology and Biophysics, School of Medicine, University of California
- Paul Contestable
- Ortho Clinical Diagnostics
- Laurence M. Corash
- Cerus Corporation
- Michael P. Busch
- Vitalant Research Institute
- Philip L. Felgner
- Department of Physiology and Biophysics, School of Medicine, University of California
- Saahir Khan
- Division of Infectious Diseases, Department of Medicine, Keck School of Medicine, University of Southern California
- DOI
- https://doi.org/10.1038/s41467-020-20095-2
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 9
Abstract
COVID-19 diagnosis is commonly performed by PCR testing, however, serologic methods are more accurate and versatile for monitoring disease burden and epidemiology. Here the authors report a protein microarray with antigens from SARS-CoV-2, SARS-CoV, MERS-CoV as well as common human respiratory viruses.