Alert! Does Prolonged Temporary Support Induce an Immunological Response?

Hira Shakoor, BA; Ahmad Abdelrehim, MD; Neville Maliakkal, BS; Staci McKean, MSN, ACNS; Caroline Harrison, MS; Johanna Van Zyl, PhD; Raksha Patel, PharmD; Shelley Hall, MD; Amit Alam, MD

JACC: Case Reports (Jun 2023)

Alert! Does Prolonged Temporary Support Induce an Immunological Response?

Hira Shakoor, BA,
Ahmad Abdelrehim, MD,
Neville Maliakkal, BS,
Staci McKean, MSN, ACNS,
Caroline Harrison, MS,
Johanna Van Zyl, PhD,
Raksha Patel, PharmD,
Shelley Hall, MD,
Amit Alam, MD

Affiliations

Hira Shakoor, BA: Baylor University Medical Center, part of Baylor Scott and White Health, Dallas, Texas, USA; Baylor Scott and White Research Institute, Dallas, Texas, USA; Address for correspondence: Hira Shakoor, Baylor Scott and White Research Institute, 3410 Worth Street, Suite 560, Dallas, Texas 75246, USA.
Ahmad Abdelrehim, MD: Baylor University Medical Center, part of Baylor Scott and White Health, Dallas, Texas, USA; Baylor Scott and White Research Institute, Dallas, Texas, USA
Neville Maliakkal, BS: Baylor University Medical Center, part of Baylor Scott and White Health, Dallas, Texas, USA; Baylor Scott and White Research Institute, Dallas, Texas, USA
Staci McKean, MSN, ACNS: Baylor University Medical Center, part of Baylor Scott and White Health, Dallas, Texas, USA; Center for Advanced Heart and Lung Disease, Dallas, Texas, USA
Caroline Harrison, MS: Baylor University Medical Center, part of Baylor Scott and White Health, Dallas, Texas, USA; Baylor Scott and White Research Institute, Dallas, Texas, USA
Johanna Van Zyl, PhD: Baylor University Medical Center, part of Baylor Scott and White Health, Dallas, Texas, USA; Baylor Scott and White Research Institute, Dallas, Texas, USA
Raksha Patel, PharmD: Baylor University Medical Center, part of Baylor Scott and White Health, Dallas, Texas, USA; Center for Advanced Heart and Lung Disease, Dallas, Texas, USA
Shelley Hall, MD: Baylor University Medical Center, part of Baylor Scott and White Health, Dallas, Texas, USA; Center for Advanced Heart and Lung Disease, Dallas, Texas, USA
Amit Alam, MD: Baylor University Medical Center, part of Baylor Scott and White Health, Dallas, Texas, USA; Center for Advanced Heart and Lung Disease, Dallas, Texas, USA

Journal volume & issue: Vol. 16
p. 101877

Abstract

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Little is known about the development of human leukocyte antigen antibodies with use of the temporary transvalvular pump 5.5 mechanical circulatory support device. This case reports a patient who developed de novo antibodies prior to his heart transplantation and remains free of any episodes of rejection post transplantation to date. (Level of Difficulty: Advanced.)

Published in JACC: Case Reports

ISSN: 2666-0849 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the circulatory (Cardiovascular) system
Website: https://www.journals.elsevier.com/jacc-case-reports

About the journal

Abstract

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