Bronchial asthma and helminth invasion: particularity of the cellular immunity

Abstract

In this review we discuss the mechanisms of human immune response modification by helminth in bronchial asthma. Helminth invasion causes increase of level to regulatory T-cells and to suppression of an allergic inflammation in bronchial asthma. Antihelminth therapy leads to decrease of level Treg cells. Deficiency or dysfunction of Treg cells can be a cause of allergic diseases.

Keywords

• инвазия opistorchis felineus
• бронхиальная астма
• иммунный ответ
• регуляторные t-клетки