TRPM2 Silencing Causes G2/M Arrest and Apoptosis in Lung Cancer Cells via Increasing Intracellular ROS and RNS Levels and Activating the JNK Pathway

• Shekoufeh Almasi,
• Clara Yu Long,
• Andra Sterea,
• Derek Richard Clements,
• Shashi Gujar,
• Yassine El Hiani

Affiliations

Shekoufeh Almasi

Departments of Biology, Faculty of Medicine, Dalhousie University, Halifax, NS, Canada

Clara Yu Long

Physiology and Biophysics, Faculty of Medicine, Dalhousie University, Halifax, NS, Canada

Andra Sterea

Physiology and Biophysics, Faculty of Medicine, Dalhousie University, Halifax, NS, Canada

Derek Richard Clements

Department of Microbiology and Immunology, Stanford University, Stanford, CA, USA

Shashi Gujar

Pathology, Faculty of Medicine, Dalhousie University, Halifax, NS, Canada; Microbiology and Immunobiology, Faculty of Medicine, Dalhousie University, Halifax, NS, Canada

Yassine El Hiani

Physiology and Biophysics, Faculty of Medicine, Dalhousie University, Halifax, NS, Canada