Ultra-deep sequencing reveals dramatic alteration of organellar genomes in Physcomitrella patens due to biased asymmetric recombination

Abstract

Masaki Odahara and Kensuke Nakamura et al. use deep paired-end sequencing to examine organellar genome recombination when homologous recombination repair genes are individually knocked out in the moss, Physcomitrella patens. Their results suggest that chloroplasts and mitochondria share a common mechanism for replication-related rearrangements.