Pakistan Armed Forces Medical Journal (Feb 2021)

EVALUATION OF PERIPAPILLARY RETINAL NERVE FIBRE LAYER AND CENTRAL MACULAR THICKNESS INADULTS WITH HYPEROPIC ANISOMETROPIC AMBLYOPIA

  • Tanveer Ahmed,
  • Khizar Niazi,
  • Sobia Usman Shah,
  • Junaid Afsar Khan,
  • Husnain Muhammad Bukhsh,
  • Muhammad Arslan Ashraf

DOI
https://doi.org/10.51253/pafmj.v71i1.3975
Journal volume & issue
Vol. 71, no. 1
pp. 162 – 66

Abstract

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Objective: To study per-papillary retinal nerve fibre layer (pRNFL) and central macular thickness (CMT) changes in adults with hyperopic anisometropic amblyopia using optical coherence tomography. Study Design: Cross sectional study. Place and Duration of Study: Combined Military Hospital, Lahore, Pakistan, from Oct 2019 to Feb 2020. Methodology: In this study 30 adults, 18-40 years of age were included who presented in our clinic with monocular poor vision. They underwent detailed ophthalmic clinical examination: including corrected and uncorrected distance visual acuity, slit lamp bio-microscopy and fundus examination with 90 diopter lens. After fulfilling criteria of anisometropic amblyopia, central maular thickness (CMT) and per-papillary retinal nerve fibre layer (pRNFL) thickness was measured by using RS-3000 SLO, NIDEK Co, Japan spectral domain optical coherence tomography device and compared the central maular thickness (CMT) and per-papillary retinal nerve fibre layer (pRNFL) thickness in amblyopic and fellow eye of same individual. Results: The mean change in per-papillary retinal nerve fibre layer (pRNFL) thickness in amblyopic eyes, 121.48 ± 4.90 μm and non amblyopic eyes was 112.92 ± 4.72 μm with statistical significance (p<0.001). The mean change in central macular thickness (CMT) in amblyopic eyes was 198.50 ± 5.30 μm and non amblyopic eyes was 206.80 ± 3.11 μm with statistical significance (p<0.001). There was significant increase in per-papillary retinal nerve fibre layer (pRNFL) thickness and significant decrease in central macular thickness (CMT) on comparing the amblyopic and the fellow eyes of the same patients. Conclusion: Central macular thickness (CMT) decreased.........................

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