The clinical significance of tumor infiltrating lymphoctyes in breast cancer: does subtype matter?

Abstract

Abstract Tumor infiltrating lymphocytes (TILs) are commonly detected in breast tumors but their bearing on disease outcome is uncertain. The importance of TILs appears to be subtype-specific and varies depending on the histologic characteristics of the tumor. As our understanding of tumorigenesis is increasing the relevance of immunobiology will become apparent.

Keywords

• Tumor infiltrating lymphocytes
• Cancer
• Immunobiology