Association of paediatric OCD with anti-thyroid antibodies and Hypovitaminosis D3 – A

Abstract

Hashimoto’s thyroiditis (HT), can present with depression, anxiety, mania, acute psychosis, dementia, loss of cognitive function and other symptoms. Case reports with obsessions and compulsions in patients with Hashimoto’s thyroiditis are few.1 We present a case report of paediatric OCD with Hashimoto’s thyroiditis and Hypovitaminosis D3 in a 13 year old girl who was brought with complaints of fear of contamination and washing rituals for last 2 years. Tetany and Hypothyroidism was diagnosed 3 months prior to the onset of illness. Investigations revealed, low Vitamin D levels, Anti TPO antibodies and Anti Thyroglobulin antibodies (ATG) positive and normal anti stroptolysin (ASO) titre. Till date no case of OCD was reported with comorbid autoimmune thyroid disorder and Vitamin D deficiency. This case highlights the need to investigate for Hypothyroidism with OCD not just to rule out Pediatric autoimmune neuropsychiatric disorders (PANDAS) but also to diagnose Hashimoto’s Thyroiditis. Vitamin D deficiency is common in patients with HT and its screening and supplementation must be considered in all patients.

Keywords

• paediatric ocd
• hashimoto’s thyroiditis
• hypovitaminosis d