Ivermectin drug induced liver injury

Mark Sonderup; Washington Mudini; Wendy Spearman

South African Medical Journal (Jun 2023)

Ivermectin drug induced liver injury

Mark Sonderup,
Washington Mudini,
Wendy Spearman

Affiliations

Mark Sonderup: Division of Hepatology and Department of Medicine, Faculty of Health Sciences, University of Cape Town and Groote Schuur Hospital
Washington Mudini: Department of Anatomical Pathology and the National Health Laboratory System, D7, University of Cape Town and Groote Schuur Hospital
Wendy Spearman: Division of Hepatology and Department of Medicine, Faculty of Health Sciences, University of Cape Town and Groote Schuur Hospital

Journal volume & issue: Vol. 113, no. 6

Abstract

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Ivermectin remains a popular, albeit unproven, therapy used in both the prevention and treatment of COVID-19. We discuss a patient who developed jaundice and a liver injury 3 weeks after initiating ivermectin for COVID prevention. Liver histology demonstrated a pattern of injury that was both portal and lobular, with a bile ductulitis as well with marked cholesasis. She was managed with low dose corticosteroids, later tapered and withdrawn. She remains well a year after presenting.

Published in South African Medical Journal

ISSN: 0256-9574 (Print); 2078-5135 (Online)
Publisher: South African Medical Association
Country of publisher: South Africa
LCC subjects: Medicine: Medicine (General)
Website: https://samajournals.co.za/index.php/samj/index

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Abstract

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