PLoS Medicine (Mar 2010)

Can animal models of disease reliably inform human studies?

  • H Bart van der Worp,
  • David W Howells,
  • Emily S Sena,
  • Michelle J Porritt,
  • Sarah Rewell,
  • Victoria O'Collins,
  • Malcolm R Macleod

DOI
https://doi.org/10.1371/journal.pmed.1000245
Journal volume & issue
Vol. 7, no. 3
p. e1000245

Abstract

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H. Bart van der Worp and colleagues discuss the controversies and possibilities of translating the results of animal experiments into human clinical trials.