Emerging Infectious Diseases (Jul 2010)

Vaccine-associated Paralytic Poliomyelitis in Immunodeficient Children, Iran, 1995–2008

  • Shohreh Shahmahmoodi,
  • Setareh Mamishi,
  • Asghar Aghamohammadi,
  • Nessa Aghazadeh,
  • Hamideh Tabatabaie,
  • Mohammad Mehdi Gooya,
  • Seyed Mohsen Zahraei,
  • Taha Mousavi,
  • Maryam Yousefi,
  • Kobra Farrokhi,
  • Masoud Mohammadpour,
  • Mahmoud Reza Ashrafi,
  • Rakhshandeh Nategh,
  • Nima Parvaneh

DOI
https://doi.org/10.3201/eid1607.091606
Journal volume & issue
Vol. 16, no. 7
pp. 1133 – 1136

Abstract

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To determine the prevalence of vaccine-associated paralytic poliomyelitis (VAPP) in immunodeficient infants, we reviewed all documented cases caused by immunodeficiency-associated vaccine-derived polioviruses in Iran from 1995 through 2008. Changing to an inactivated polio vaccine vaccination schedule and introduction of screening of neonates for immunodeficiencies could reduce the risk for VAPP infection.

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