Viral persistence: immunologic and molecular-genetic aspects of pathogenesis

Abstract

In the article a view of investigators on the modern understanding of long-term viral persistence forming mechanisms on cellular and molecular levels has been presented. A question on the role of persistent virus in the induction of changes in cellular differentiation character, of chromosome apparatus and of apoptosis of peripheral blood lymphocytes has been discussed.

Keywords

• вирусная персистенция
• лимфоцит
• иммунофенотип
• хромосомный аппарат
• апоптоз