Psoriasis: Not just skin deep

Abstract

Psoriasis is a multisystem, chronic, and incapacitating inflammatory disease, which can be associated with comorbidities of varying severity. These comorbidities can have a notable influence on the quality of life and result in mortality in rare instances. Although the disorders represent separate entities, the underlying chronic inflammatory nature of psoriasis and overlapping pathogenic pathways explain most of these associations. These disorders often present years after the initiation of psoriasis and are usually associated with extensive disease. In this review article, we discuss the various comorbidities associated with psoriasis as their early recognition will enable timely intervention, influence management options, and go a long way in improving the quality of life and life expectancy of these patients.

Keywords

• Psoriasis
• comorbidities
• metabolic syndrome