A rare case of acute myeloid leukemia with der(1)t(1;19)(p13;p13.1)

Meghan McAlice; Munaza Gohar; Ahmed Alshaban; Attilio Orazi; Vijay Tonk; Santosh Chavali; Sahil Tonk; Sumit Gaur

Leukemia Research Reports (Jan 2019)

A rare case of acute myeloid leukemia with der(1)t(1;19)(p13;p13.1)

Meghan McAlice,
Munaza Gohar,
Ahmed Alshaban,
Attilio Orazi,
Vijay Tonk,
Santosh Chavali,
Sahil Tonk,
Sumit Gaur

Affiliations

Meghan McAlice: Department of Internal Medicine, Texas Tech University Health Sciences Center, El Paso, TX, United States; Corresponding author.
Munaza Gohar: Department of Internal Medicine, Texas Tech University Health Sciences Center, El Paso, TX, United States
Ahmed Alshaban: Department of Internal Medicine, Texas Tech University Health Sciences Center, El Paso, TX, United States
Attilio Orazi: Department of Pathology, Texas Tech University Health Sciences Center, El Paso, TX, United States
Vijay Tonk: Department of Pediatrics, Texas Tech University Health Sciences Center, Lubbock, TX, United States
Santosh Chavali: Department of Pediatrics, Texas Tech University Health Sciences Center, Lubbock, TX, United States
Sahil Tonk: Department of Pediatrics, Texas Tech University Health Sciences Center, Lubbock, TX, United States
Sumit Gaur: Department of Internal Medicine, Texas Tech University Health Sciences Center, El Paso, TX, United States

Journal volume & issue: Vol. 12

Abstract

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We present a case of acute myeloid leukemia with der(1)t(1;19)(p13;p13.1) translocation and RUNX1 mutation. A literature review summarizing the clinical, pathological, and molecular features of the published cases is also presented. Keywords: Acute myeloid leukemia, AML, RUNX1, Hand-mirror blasts, t(1;19)

Published in Leukemia Research Reports

ISSN: 2213-0489 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: http://www.journals.elsevier.com/leukemia-research-reports/

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