Elderly female with Autoimmune hemolytic anemia

Journal of Mid-Life Health. 2015;6(3):132-133 DOI 10.4103/0976-7800.165596


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Journal Title: Journal of Mid-Life Health

ISSN: 0976-7800 (Print); 0976-7819 (Online)

Publisher: Wolters Kluwer Medknow Publications

Society/Institution:  Indian Menopause Society

LCC Subject Category: Medicine: Gynecology and obstetrics | Medicine: Internal medicine: Special situations and conditions: Geriatrics

Country of publisher: India

Language of fulltext: English

Full-text formats available: PDF, HTML, ePUB



Anupam Dey


Double blind peer review

Editorial Board

Instructions for authors

Time From Submission to Publication: 43 weeks


Abstract | Full Text

Autoimmune hemolytic anemia (AIHA) is a rare disease with an estimated prevalence of around 17/100,000. It is often difficult to diagnose and treat AIHA, especially in elderly. A 60-year-old female was admitted with the complaints of low grade fever, on-off for 6 months, progressive fatigue and dyspnea on exertion. She was transfused with three units of blood within these 6 months. Examination revealed pallor, edema, hemic murmur, and palpable liver. Hb was 2.9 gm%, T Bil 5.2 mg/dl, ESR 160 mm, and reticulocyte count 44.05%. Direct Coombs test was positive, anti-nuclear antibody (ANA) and Anti ds DNA were positive. A diagnosis of systemic lupus erythematosus (SLE) with AIHA was considered and patient was transfused with two units of packed red cells and put on steroid (prednisolone) at 1 mg/kg body weight daily. After 3 weeks, her Hb had increased to 10.4 gm% with gross clinical improvement.