Peculiarities of Lipid Metabolism in Children with Metabolic Syndrome

Abstract

Peculiarities of blood lipids in children with metabolic syndrome were studied. We observed 139 children aged 9 to 18 years, who formed two groups: 1st group — 85 children with metabolic syndrome on the background of abdominal obesity, 2nd group — 54 children with normal body weight. We have carried out anthropometry, defined levels of total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, very low-density lipoprotein cholesterol, triglycerides, blood pressure measured. It is found that signs of dyslipidemia were significantly elevated levels of total cholesterol, low-density lipoprotein cholesterol, very low-density lipoprotein cholesterol, triglycerides and ratio of non-high-density lipoprotein cholesterol, total cholesterol/high-density lipoprotein cholesterol, atherogenic index, which should be used as markers in the diagnosis of metabolic syndrome in children. Relative increase of high-density lipoprotein cholesterol fractions, possibly, must be considered as compensatory reaction in response to an increase of proatherogenic cholesterol fractions with a view to their normalization.

Keywords

• lipid metabolism
• metabolic syndrome
• children