A Convenient Synthesis towards 2-Bromo-2-(methoxy(phenyl)methyl)malononitrile and 2-Iodo-2-(methoxy(phenyl)methyl)malononitrile
Jialuo Chen,
Lili Duan,
Kunming Liu,
Jin-Biao Liu
Affiliations
Jialuo Chen
Jiangxi Provincial Key Laboratory of Functional Molecular Materials Chemistry, Faculty of Materials, Metallurgy and Chemistry, Jiangxi University of Science and Technology, 86 Hongqi Road, Ganzhou 341000, China
Lili Duan
Jiangxi Provincial Key Laboratory of Functional Molecular Materials Chemistry, Faculty of Materials, Metallurgy and Chemistry, Jiangxi University of Science and Technology, 86 Hongqi Road, Ganzhou 341000, China
Kunming Liu
Jiangxi Provincial Key Laboratory of Functional Molecular Materials Chemistry, Faculty of Materials, Metallurgy and Chemistry, Jiangxi University of Science and Technology, 86 Hongqi Road, Ganzhou 341000, China
Jin-Biao Liu
Jiangxi Provincial Key Laboratory of Functional Molecular Materials Chemistry, Faculty of Materials, Metallurgy and Chemistry, Jiangxi University of Science and Technology, 86 Hongqi Road, Ganzhou 341000, China
This short note elaborates a concise protocol for the synthesis of two novel vicinal haloethers bearing a malonontrile group, 2-bromo-2-(methoxy(phenyl)methyl)malononitrile (1) and 2-iodo-2-(methoxy(phenyl)methyl)malononitrile (2). The structures of the synthesized compounds were confirmed by 1H, 13C-NMR spectroscopy. The final products indicate that methanol not only acts as solvent but also participates in and dominates the reaction result.
