A Convenient Synthesis towards 2-Bromo-2-(methoxy(phenyl)methyl)malononitrile and 2-Iodo-2-(methoxy(phenyl)methyl)malononitrile

Jialuo Chen; Lili Duan; Kunming Liu; Jin-Biao Liu

doi:10.3390/M1373

Molbank (May 2022)

A Convenient Synthesis towards 2-Bromo-2-(methoxy(phenyl)methyl)malononitrile and 2-Iodo-2-(methoxy(phenyl)methyl)malononitrile

Jialuo Chen,
Lili Duan,
Kunming Liu,
Jin-Biao Liu

Affiliations

Jialuo Chen: Jiangxi Provincial Key Laboratory of Functional Molecular Materials Chemistry, Faculty of Materials, Metallurgy and Chemistry, Jiangxi University of Science and Technology, 86 Hongqi Road, Ganzhou 341000, China
Lili Duan: Jiangxi Provincial Key Laboratory of Functional Molecular Materials Chemistry, Faculty of Materials, Metallurgy and Chemistry, Jiangxi University of Science and Technology, 86 Hongqi Road, Ganzhou 341000, China
Kunming Liu: Jiangxi Provincial Key Laboratory of Functional Molecular Materials Chemistry, Faculty of Materials, Metallurgy and Chemistry, Jiangxi University of Science and Technology, 86 Hongqi Road, Ganzhou 341000, China
Jin-Biao Liu: Jiangxi Provincial Key Laboratory of Functional Molecular Materials Chemistry, Faculty of Materials, Metallurgy and Chemistry, Jiangxi University of Science and Technology, 86 Hongqi Road, Ganzhou 341000, China

DOI: https://doi.org/10.3390/M1373
Journal volume & issue: Vol. 2022, no. 2
p. M1373

Abstract

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This short note elaborates a concise protocol for the synthesis of two novel vicinal haloethers bearing a malonontrile group, 2-bromo-2-(methoxy(phenyl)methyl)malononitrile (1) and 2-iodo-2-(methoxy(phenyl)methyl)malononitrile (2). The structures of the synthesized compounds were confirmed by 1H, 13C-NMR spectroscopy. The final products indicate that methanol not only acts as solvent but also participates in and dominates the reaction result.

Published in Molbank

ISSN: 1422-8599 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Chemistry: Inorganic chemistry
Website: https://www.mdpi.com/journal/molbank

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