Comparison of nutritional parameters after abo incompatible living donor renal transplantation

Abstract

The prevalence of malnutrition is high in patients on maintenance dialysis treatment in relation to low protein and energy intakes, metabolic disorders. We investigated the evolution of nutritional status during the first year after ABO incompatible living donor kidney transplantation (ABOI-LKT) in our hospital through assessment of chemical markers. A total of 16 kidney transplant recipients were followed during the first post-transplant year. Biochemical nutritional markers were assessed at 12 months later after ABOI-LKT. Differences in the means between the pre-transplant and post-transplant chemical markers were evaluated by paired Student’s t-test. Pre-transplant Post-transplant p value Body weight (kg) 57.74 ± 8.00 54.43 ± 7.62 0.00 S. hemoglobin (g/dL) 10.44 ± 1.32 12.04 ± 1.87 0.03 S. BUN (mg/dL) 46.55 ± 22.52 18.13 ± 5.88 0.00 S. creatinine (mg/dL) 8.06 ± 3.39 1.15 ± 0.57 0.00 S. calcium (mg/dL) 8.70 ± 1.10 9.12 ± 0.72 0.04 S. phosphate (mg/dL) 5.20 ± 2.05 2.50 ± 1.05 0.00 S. albumin (g/dL) 3.59 ± 0.52 4.06 ± 0.33 0.00 S. globulin (g/dL) 2.83 ± 0.52 2.49 ± 0.35 0.00 HDL (mg/dL) 47.80 ± 12.36 63.45 ± 16.97 0.00 Total bilirubin (mg/dL) 0.45 ± 0.13 0.78 ± 0.39 0.00 AST (IU/L) 14.20 ± 6.30 20.90 ± 8.78 0.01 ALT (IU/L) 12.75 ± 5.63 22.10 ± 12.53 0.01 By the end of the first year, serum hemoglobin, calcium, albumin, HDL, bilirubin, AST, ALT were increased statistically. But serum phosphate, globulin were decreased statistically. In conclusion, successful ABO incompatible living donor kidney transplantation would restore a normal nutritional status even though the patients were performed plasmapheresis during the pre-transplant period.