Nature Communications (Jul 2018)

TCM visualizes trajectories and cell populations from single cell data

  • Wuming Gong,
  • Il-Youp Kwak,
  • Naoko Koyano-Nakagawa,
  • Wei Pan,
  • Daniel J. Garry

DOI
https://doi.org/10.1038/s41467-018-05112-9
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 8

Abstract

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Time series single cell expression data has large variance between time points and is challenging for analysis. Here, the authors develop a new dimension reduction and data visualization tool for large scale temporal scRNA-seq data which identifies trajectories and subpopulations.