Prevalence and coexistence of type 2 inflammatory diseases

Abstract

Abstract Background Type 2 inflammation has been described as a pathophysiological basis common to some diseases, such as atopic dermatitis (AD), chronic rhinosinusitis with nasal polyps, and asthma (CRSwNP). Objective The present study used population‐based prevalence in Catalonia to analyse the coexistence of type 2 inflammatory diseases in patients primarily diagnosed with the above mentioned conditions. Results We found a high degree of coexistence of type 2 inflammatory diseases among these patients, with the prevalence being higher in the severe forms, except for AD. For the severe forms of primary diseases, the proportion of patients with coexisting type 2 inflammatory diseases (severe or non‐severe) was 16.2% for AD, 19.8% for asthma, and a striking 62.4% for CRSwNP. This patient population has the highest proportion of coexisting type 2 inflammatory diseases, both severe (48.9%) and non‐severe (13.5%). Conclusion Our findings have significant implications for the management of patients with AD, asthma, and CRSwNP.

Keywords

• asthma
• atopic dermatitis
• epidemiology
• Nasal polyps
• population‐based
• prevalence Catalonia