«Propofol infusion syndrome» - case in a child of 10 years

Abstract

A case description of a serious adverse reaction «propofol infusion syndrome» (PRIS), the existence of which has not been previously described in the literature - neurotoxic effect of deep coma is present. The reaction occurred in a child aged 10 years on the background of prolonged infusion of propofol and excess dose. The data of the literature regarding the etiology and pathogenesis of this syndrome, as well as possible factors responsible for features of the course in the present clinical case are presented.

Keywords

• нежелательная реакция
• пропофол
• нейротоксическое действие
• кома
• ребенок
• adverse reaction
• propofol
• neurotoxicity
• coma
• child