mSphere (Feb 2021)

Glucose-6-Phosphate Acts as an Extracellular Signal of SagS To Modulate <i>Pseudomonas aeruginosa</i> c-di-GMP Levels, Attachment, and Biofilm Formation

  • Soyoung Park,
  • Jozef Dingemans,
  • Madison Gowett,
  • Karin Sauer

DOI
https://doi.org/10.1128/mSphere.01231-20
Journal volume & issue
Vol. 6, no. 1

Abstract

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Pathogens sense and respond to signals and cues present in their environment, including host-derived small molecules to modulate the expression of their virulence repertoire. Here, we demonstrate that the opportunistic pathogen Pseudomonas aeruginosa