Open Medicine (Mar 2025)

The correlation between epithelial–mesenchymal transition classification and MMP2 expression of circulating tumor cells and prognosis of advanced or metastatic nasopharyngeal carcinoma

  • Wang Xiaoju,
  • Zhang Yuxin,
  • Wang Yiqing,
  • Shi Lei,
  • Yuan Caiqin,
  • Yin Wei,
  • Teng Yaoshu,
  • Li Jing,
  • Mao Yanjiao

DOI
https://doi.org/10.1515/med-2024-1074
Journal volume & issue
Vol. 20, no. 1
pp. 840 – 59

Abstract

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Epithelial–mesenchymal transition (EMT) and circulating tumor cells (CTCs) are key prognostic factors in nasopharyngeal carcinoma (NPC). However, the role of EMT status in CTCs for predicting outcomes in advanced NPC treated with radiotherapy after induction chemotherapy remains unclear.

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