850 Dual blockade of the EP2 and EP4 PGE2 receptors with TPST-1495 is an optimal approach for drugging the prostaglandin pathway

• Sam Whiting,
• Amanda Enstrom,
• Brian Francica,
• Thomas Dubensky,
• Chan Whiting,
• Dingzhi Wang,
• Justine Lopez,
• Anja Holtz,
• Dave Freund

Affiliations

Sam Whiting

Aff1 VentiRx Pharmaceuticals Seattle WA USA

Amanda Enstrom

Aff187 grid.417411.6Aduro Biotech, Inc. Berkeley CA USA

Brian Francica

Aff531 grid.21107.350000000121719311Johns Hopkins University School of Medicine Baltimore MD USA

Thomas Dubensky

Aff1 grid.417411.6Aduro BioTech Berkeley CA USA

Chan Whiting

Aff1 grid.417411.6Aduro BioTech, Inc. Berkeley CA USA

Dingzhi Wang

Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Justine Lopez

1Tempest Therapeutics, Berkeley, CA, USA

Anja Holtz

1Tempest Therapeutics, Berkeley, CA, USA

Dave Freund

1Tempest Therapeutics, Berkeley, CA, USA