Chemosensors (Feb 2025)
Detection of Novichok and V-Group Nerve Agents by Chemosensors Containing Nile Blue Chromophore
Abstract
This paper presents the results of experiments aiming for the detection and differentiation of selected nerve agents of the Novichok and V-group using simple strip detectors containing colourimetric indicator, specifically chemosensor Nile Blue A, immobilized in cellulose matrix. In all experimental modifications, the contact of the active zone of the strip detector and respective nerve agent excited an immediate development of significant colouration visible to the naked eye. Alkaline solutions containing various hydroxides, carbonates and bicarbonates, and/or chloramine B were used to demonstrate the relevant reaction. The proposed strip detectors indicate a promising approach towards the development of low-cost, easily portable, and usable means of detection of the respective nerve agents.
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