The autophagy research in electron microscopy

Abstract

Abstract Autophagy, a highly conserved process of eukaryotic cellular recycling, plays an important role in cell survival and maintenance. Dysfunctional autophagy contributes to the pathologies of many human diseases. Many studies have attempted to clarify the process of autophagy. Here, we review morphological studies of autophagy involving electron microscopy.

Keywords

• Electron microscopy
• Autophagic flux
• CLEM
• Immuno-gold
• Cryo-EM