Reproducibility of 2D versus 3D radiomics for quantitative assessment of fetal lung development: a retrospective fetal MRI study

Abstract

Key points Standardised fetal MRI delivers reproducible quantitative whole lung radiomics features. 2D lung ROI radiomics features are not representative of the whole fetal lung. Whole lung radiomics features are better reproducible than 2D ROI features. Whole lung radiomics features are more sensitive to subtle differences between normal and pathological fetal lung development compared to 2D lung ROI features. Fetal MRI whole lung radiomics may improve non-invasive in-vivo lung development assessment.

Keywords

• Magnetic resonance imaging
• Fetal development
• Lung
• Reproducibility of results
• Radiomics