Indian Journal of Ophthalmology (Jan 1988)
A comparative study of the effect of antiprostaglandins and steroids on aphakic cystoid macular oedema
Abstract
The present double masked, randomized and placebo control study was carried out to compare the effects of steroids and an antiprostaglandin drug on aphakic cystoid macular oedema (ACME) in 60 cases who underwent uneventful intracapsular lens extraction. These 60 eyes were equally divided into three groups depending on the type of prophylactic eye drop instilled viz. Placebo group (I), steroid group (11) and in-domethacin group (III). Angiographic incidence of ACME observed in groups I, II and III was 40%, 10% and I0%, respectively. It is concluded that prophylactic treatment with topical steroids or indomethacin have a definite role to play in reducing the incidence as well as severity of ACME. Hence, their use is recommended for the prophylaxis- of ACHE. However, to justify the superiority of indomethacin or dexamethasone over each other a large and long term compara-tive studs is suggested.
